Harnessing Discomfort for Healing — Pressing on the Pain Side (Chapter 7 of Dopamine Nation)
Harnessing Discomfort for Healing — Pressing on the Pain Side (Chapter 7 of Dopamine Nation)

Can seeking discomfort actually improve mental health and support addiction recovery? Chapter 7 of Dopamine Nation: Finding Balance in the Age of Indulgence by Anna Lembke, MD, explores the paradoxical benefits of intentionally “pressing on the pain side” of the pleasure-pain balance. Through patient stories, historical context, and modern neuroscience, this chapter demonstrates how controlled exposure to discomfort—such as cold-water therapy and other hormetic practices—can lead to profound healing, growth, and even joy.
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Michael’s Story: Overcoming Addiction through Cold-Water Therapy
One of the chapter’s central stories is Michael’s transformation from drug addiction to recovery through cold-water immersion. Starting with cold showers and progressing to ice baths, Michael discovered that the controlled pain of cold exposure actually improved his mood and became a cornerstone of his well-being. His journey highlights how embracing discomfort, rather than avoiding it, can be a powerful catalyst for recovery.
The Science and History of Cold-Water Therapy
Cold-water therapy isn’t a new idea—its roots stretch back to ancient Greece and influential figures like Vincenz Priessnitz in early 20th-century Europe. Modern research shows that cold immersion increases levels of monoamine neurotransmitters (dopamine, norepinephrine, serotonin), boosting mood, motivation, and alertness. The deliberate shock to the system stimulates the pleasure-pain balance, leading to both physiological and psychological benefits.
The Pleasure-Pain Balance and Hormesis
Central to this chapter is the concept of hormesis: the idea that small, controlled doses of stress or pain produce long-term benefits. Exercise is a classic example—initial discomfort leads to improved physical and mental health. Other hormetic practices discussed include acupuncture, low-dose naltrexone, and even electroconvulsive therapy for severe mental illness. Historical “heroic therapies” such as bloodletting and blistering reflect earlier, less nuanced attempts to harness these effects.
Modern Applications and Personal Growth
Today, structured challenges like ultramarathons and even free solo climbing tap into the hormetic healing principle. Research and real-world examples suggest that humans (and even animals) naturally seek out manageable discomfort for the intrinsic rewards it brings. Social and psychological experiments—like facing social anxiety head-on—can promote resilience, adaptability, and greater overall satisfaction.
The Right Amount of Pain: A Pathway to Joy
While too much pain is damaging, the right amount, introduced thoughtfully, triggers a healing response and increases our capacity for pleasure. Lembke emphasizes that the key is to find a healthy balance, using deliberate discomfort as a tool for growth and emotional regulation.
Glossary of Key Terms
- Euphoric: Intense excitement and happiness.
- Hormesis: The beneficial effects of small doses of stress or pain.
- Monoamine Neurotransmitters: Includes dopamine, norepinephrine, and serotonin—regulating mood and motivation.
- Homeostatic Set Point: The body’s baseline level for stability and balance.
- Hedonic Set Point: The baseline for happiness or well-being.
- Heroic Therapies: Historical drastic treatments, such as bloodletting, once used for healing.
- Hormetic Healing: Adaptive healing triggered by manageable doses of stress or discomfort.
Conclusion: Embracing Discomfort for a Balanced Life
Chapter 7 of Dopamine Nation reframes discomfort not as something to avoid, but as an essential ingredient in healing and growth. Whether through cold-water immersion, exercise, or psychological challenges, pressing on the pain side helps restore balance and enhances our appreciation for pleasure. Anna Lembke, MD, provides a blueprint for using hormetic stress to build resilience, personal satisfaction, and a deeper sense of well-being.
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