Renal Disorders, Dialysis, & Kidney Care — Anatomy, AKI, CKD, and NCLEX Nursing Interventions | Chapter 51: Saunders NCLEX-PN Review
Renal Disorders, Dialysis, & Kidney Care — Anatomy, AKI, CKD, and NCLEX Nursing Interventions | Chapter 51: Saunders NCLEX-PN Review
Chapter 51 of Saunders Comprehensive Review for the NCLEX-PN® Examination (7th Edition) by Linda Anne Silvestri and Angela E. Silvestri provides an in-depth study of the renal system, from kidney anatomy and nephron function to complex renal disorders, dialysis procedures, and transplant care. This chapter emphasizes fluid and electrolyte balance, diagnostic interpretation, and NCLEX-priority nursing interventions for safe renal care.
Watch the lecture above for a complete renal system review, then follow the detailed study notes below to prepare for the NCLEX-PN exam.

Kidney Anatomy & Physiology
- Nephron structure — glomerulus, Bowman’s capsule, tubules
- Functions — filtration, reabsorption, secretion, urine formation
- Hormonal regulation — ADH, aldosterone, renin-angiotensin-aldosterone system
- pH balance — bicarbonate buffer system, acid-base homeostasis
Diagnostic Tests
- Serum creatinine, BUN, GFR — primary renal function markers
- Urinalysis — protein, specific gravity, casts
- Imaging — KUB, renal ultrasound, IV pyelogram (check iodine allergy)
- Renal biopsy — bleeding precautions and post-procedure care
Acute Kidney Injury (AKI)
- Causes — prerenal, intrarenal, postrenal
- Phases — oliguric, diuretic, recovery
- Nursing care — fluid balance, electrolyte management, renal diet
Chronic Kidney Disease (CKD)
- Stages — from mild damage to end-stage renal disease
- Complications — anemia, bone disease, cardiovascular issues
- Uremic syndrome — nitrogen retention, neurologic changes, pruritus
Dialysis Therapies
- Hemodialysis: AV fistula/graft care, infection prevention, fluid removal
- Peritoneal dialysis: CAPD, CCPD; dialysate exchange steps, peritonitis prevention
- CRRT — for critically ill patients with unstable hemodynamics
Electrolyte Imbalances in Renal Disorders
- Hyperkalemia — peaked T waves on ECG, insulin/glucose or calcium gluconate for treatment
- Hypermagnesemia — respiratory depression, reflex loss
- Hypocalcemia — muscle spasms, Chvostek’s and Trousseau’s signs
Urinary & Prostatic Conditions
- UTI, cystitis, urethritis, pyelonephritis — causes, symptoms, antibiotics
- BPH — urinary retention, TURP care, prevention of TURP syndrome
Renal Calculi
- Types — calcium, uric acid, struvite, cystine
- Prevention — hydration, dietary changes, control of underlying conditions
- Treatments — lithotripsy, surgery, nephrostomy tube care
Kidney Transplantation
- Donor-recipient matching, surgery steps
- Immunosuppressive therapy — cyclosporine, tacrolimus
- Rejection signs — fever, graft tenderness, decreased urine output
NCLEX Nursing Priorities
- Strict fluid intake and output monitoring
- Daily weights for fluid balance
- Electrolyte lab interpretation and correction
- Infection prevention in all catheter and access care
- Comprehensive patient education — diet, activity, medication adherence
Conclusion
Renal disorders demand precise assessment, timely interventions, and expert client teaching. Chapter 51 provides the NCLEX-PN candidate with the knowledge needed to manage AKI, CKD, dialysis, and transplant care with confidence.
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View the full Saunders Comprehensive Review for the NCLEX-PN® Examination (7th Edition) playlist here: Complete NCLEX-PN Review Playlist
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