Acid–Base Reactions in Organic Chemistry — ARIO, pKa, and Reaction Prediction Explained | Chapter 3 of Klein Organic Chemistry as a Second Language
Acid–Base Reactions in Organic Chemistry — ARIO, pKa, and Reaction Prediction Explained | Chapter 3 of Klein Organic Chemistry as a Second Language Acid–base chemistry is the backbone of organic reactivity. In Chapter 3 of Organic Chemistry as a Second Language: First Semester Topics by David Klein, students learn how proton transfer reactions are governed by charge stability, electron distribution, and predictable structural trends. This chapter provides a conceptual toolkit for determining which protons are acidic, which bases are stable, and how to predict the direction of equilibrium—skills that reappear constantly in mechanisms throughout the course. 🎥 Watch the video above for a clear walkthrough of ARIO, pKa values, and how acid–base principles guide reaction prediction in organic chemistry. Why Acid–Base Reactions Matter Nearly every organic reaction involves acid–base behavior at some stage, whether explicit or hidden within a mechanism. Chapter 3 emphasizes t...