SN1 vs SN2 Substitution Reactions Explained — Mechanisms, Factors, and Stereochemistry | Chapter 9 of Klein Organic Chemistry as a Second Language
SN1 vs SN2 Substitution Reactions Explained — Mechanisms, Factors, and Stereochemistry | Chapter 9 of Klein Organic Chemistry as a Second Language Substitution reactions are among the most important and most tested reactions in introductory organic chemistry. In Chapter 9 of Organic Chemistry as a Second Language: First Semester Topics by David Klein, students learn how to distinguish between SN1 and SN2 mechanisms and predict which pathway will dominate under a given set of conditions. This chapter synthesizes everything learned so far—mechanisms, stereochemistry, carbocations, nucleophiles, and solvents—into a practical decision-making framework that applies across the rest of the course. 🎥 Watch the video above for a clear, step-by-step breakdown of SN1 and SN2 substitution reactions and how to confidently predict reaction outcomes. What Are Substitution Reactions? In a substitution reaction, one group attached to a carbon atom—the leaving group—is replaced by anoth...